Silvestrol (aglycone) SMI-4 Formula: C18H17FN4O

Formula: C18H17FN4O

is a novel potent and selective PKCθ inhibitor

InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11

Sutcliffe P

Silvestrol (aglycone) SMI-4 Formula: C18H17FN4OSilvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc LUC and tub LUC luciferase reporter protein translation, respectively. Anti cancer activity. Product information CAS Number: 960365 65 5 Molecular Weight: 478. 49 Formula: C27H26O8 Chemical Name: methyl (2S,3R,4R,5S,6R) 2,3,10 trihydroxy 12 methoxy 6 (4 methoxyphenyl) 5 phenyl 7 oxatricyclo[6. 4. 0. 0,]dodeca